Rampage driven by a scream (3,4)
I believe the answer is:
run riot
'a scream' is the definition.
I know nothing about this answer so I cannot tell whether it can be defined by this definition.
'rampage driven by' is the wordplay.
'rampage' becomes 'riot' (rioting is a kind of rampaging).
'driven' becomes 'run' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'by' is a charade indicator (letters next to each other).
'riot' after 'run' is 'RUN RIOT'.
Can you help me to learn more?
(Other definitions for run riot that I've seen before include "Lose control" , "Raise hell" , "behave in unrestrained way" , "Act wildly" , "Go berserk" .)