Ran one in road (5)
I believe the answer is:
raced
'ran' is the definition.
('race' can be a synonym of 'run')
'one in road' is the wordplay.
'one' becomes 'ace' ('ace' can be a synonym of 'one').
'in' indicates putting letters inside.
'road' becomes 'rd' (abbreviation).
'ace' inserted within 'rd' is 'RACED'.
(Other definitions for raced that I've seen before include "Rushed" , "speeded" , "Operated at excessive speed" , "Took part in speed contest" , "Took part in competition of speed" .)