Rascal with voice damage (6)
I believe the answer is:
impair
'damage' is the definition.
(impairing is a kind of damaging)
'rascal with voice' is the wordplay.
'rascal' becomes 'imp' (synonyms).
'with' means one lot of letters go next to another.
'voice' becomes 'air' (both can mean to express something).
'imp'+'air'='IMPAIR'
(Other definitions for impair that I've seen before include "Weaken, damage" , "'Mar, damage (6)'" , "Cause weakening of, damage" , "Spoil, degrade" , "Hobble" .)