React drunkenly after noon drink (6)
I believe the answer is:
nectar
'drink' is the definition.
(nectar is a kind of drink)
'react drunkenly after noon' is the wordplay.
'drunkenly' indicates an anagram.
'after' means one lot of letters go next to another.
'noon' becomes 'n' (**).
'react' anagrammed gives 'ectar'.
'ectar' put after 'n' is 'NECTAR'.
(Other definitions for nectar that I've seen before include "Heavenly drink, may create trance" , "That's sweet" , "Drink of the gods in Greek myth" , "Beverage of the gods" , "Heavenly brew" .)