Real ingenue abused (7)
I believe the answer is:
genuine
'real' is the definition.
(similar in meaning)
'ingenue abused' is the wordplay.
'abused' indicates anagramming the letters.
'ingenue' is an anagram of 'GENUINE'.
(Other definitions for genuine that I've seen before include "Native" , "Sincere, honest" , "Sincere; authentic" , "Not fake or counterfeit" , "'Real, unfeigned (7)'" .)