Really worried, having lost pound in advance (5)
I believe the answer is:
early
'in advance' is the definition.
('early' can be similar in meaning to 'in advance')
I don't understand how the remainder of the clue works.
Can you help me to learn more?
(Other definitions for early that I've seen before include "sooner than expected" , "Prematurely" , "Premature" , "before anyone else?" , "Before the expected time" .)