Reason for fatigue (4)
I believe the answer is:
toil
(Other definitions for toil that I've seen before include "Hard physical work" , "Drudgery" , "Work hard and long" , "Work hard, labour" , "Work extremely hard" .)
I believe the answer is:
toil
(Other definitions for toil that I've seen before include "Hard physical work" , "Drudgery" , "Work hard and long" , "Work hard, labour" , "Work extremely hard" .)