Refusal by wife to enter affluent city (7)
I believe the answer is:
norwich
'city' is the definition.
(I've seen this before)
'refusal by wife to enter affluent' is the wordplay.
'refusal' becomes 'no' (it's a no).
'by' says to put letters next to each other.
'wife' becomes 'w' (abbreviation).
'to enter' means one lot of letters goes inside another.
'affluent' becomes 'rich' (similar in meaning).
'w' going inside 'rich' is 'rwich'.
'no'+'rwich'='NORWICH'
(Other definitions for norwich that I've seen before include "City on the River Wensum" , "Cathedral city" , "English city" , "Largest city in East Anglia" , "Juliana of - (Revelations of Divine Love)" .)