Region of NE France (8)
I believe the answer is:
lorraine
'region of ne france' is the definition.
(I've seen this before)
This is the entire clue.
(Other definitions for lorraine that I've seen before include "See 14" , "part of France" , "Area of France after which a style of cross is named" , "Region linked to Alsace" , "French region, cross" .)