Region of the Far East (4)
I believe the answer is:
area
'region' is the definition.
(I know that region can be written as area)
'of the far east' is the wordplay.
'of' indicates the answer is hidden within the clue.
'AREA' can be found hidden inside 'far east'.
(Other definitions for area that I've seen before include "Patch" , "Geographical region" , "Region, zone" , "Speaking formally to (someone)" , "Space for a specific purpose, say picnic" .)