Region suffering neglect (6)
I believe the answer is:
ignore
'neglect' is the definition.
(neglect can mean to ignore)
'region suffering' is the wordplay.
'suffering' is an anagram indicator.
'region' anagrammed gives 'IGNORE'.
(Other definitions for ignore that I've seen before include "Refuse to notice or acknowledge" , "Blank" , "Pay no attention to, disdain" , "Turn a blind eye to" , "Pay no attention to, disregard" .)