Crossword Genius

Regret American using informal address? (6)

Ross

I believe the answer is:

missus

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'informal address?' is the definition.
Although both the answer and definition are singular nouns, I don't understand how they can define each other.

'regret american' is the wordplay.
'regret' becomes 'miss' (I am not sure about this - if you are sure you should believe this answer much more).
'american' becomes 'US' (United States).
'miss'+'us'='MISSUS'

'using' acts as a link.

Can you help me to learn more?

(Other definitions for missus that I've seen before include "trouble and strife" , "Wife (colloquial)" , "Dutch American" , "Wife (informal)" , "As partner" .)

I've seen this clue in The Irish Times.
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