Relatives might make scene about one (6)
I believe the answer is:
nieces
'relatives' is the definition.
(niece is a kind of relative)
'make scene about one' is the wordplay.
'make' indicates an anagram.
'about' indicates putting letters inside.
'one' becomes 'i' (Roman numeral).
'scene' with letters rearranged gives 'neces'.
'neces' placed around 'i' is 'NIECES'.
'might' is the link.
(Other definitions for nieces that I've seen before include "Relative girls" , "They're family" , "Relations" , "Scene I set up for relatives" , "Young female relatives" .)