Relevance of net price uncertain around northeast (10)
I believe the answer is:
pertinence
'relevance' is the definition.
(pertinence is a kind of relevance)
'net price uncertain around northeast' is the wordplay.
'uncertain' indicates an anagram.
'around' means one lot of letters goes inside another.
'northeast' becomes 'ne' ('NE' can be a synonym of 'northeast').
'net'+'price'='netprice'
'netprice' with letters rearranged gives 'pertince'.
'pertince' enclosing 'ne' is 'PERTINENCE'.
'of' is the link.
(Other definitions for pertinence that I've seen before include "Relevance" , "fitness" , "Applicability" , "to the point" .)