Religion in Mali's unorthodox (5)
I believe the answer is:
islam
'religion' is the definition.
(Islam is an example)
'mali's unorthodox' is the wordplay.
'unorthodox' indicates an anagram.
'malis' anagrammed gives 'ISLAM'.
'in' is the link.
(Other definitions for islam that I've seen before include "Mails to great eastern religion" , "Adherents of a religion" , "Creed" , "Belief" , "Religion based on Muhammad's teachings" .)