Renaissance artist's Doctor Swallowing Midge (5)
I believe the answer is:
durer
'renaissance artist's' is the definition.
(I've seen this before)
'doctor swallowing midge' is the wordplay.
'doctor' becomes 'dr' (abbreviation).
'swallowing' is an insertion indicator.
'midge' becomes 'Ure' (music producer Midge Ure).
'dr' enclosing 'ure' is 'DURER'.
(Other definitions for durer that I've seen before include "Old master" , "Albrecht -, fifteenth to sixteenth century German artist" , "Albrecht -, C15-16 German artist" , "Renaissance painter" , "German artist, d. 1528" .)