Represent guys holding answer (4)
I believe the answer is:
mean
'represent' is the definition.
(both can mean to signify)
'guys holding answer' is the wordplay.
'guys' becomes 'men' (guy can mean a man).
'holding' is an insertion indicator.
'answer' becomes 'a' (abbreviation eg in Q and A).
'men' enclosing 'a' is 'MEAN'.
(Other definitions for mean that I've seen before include "Average or mingy" , "Scrooge?" , "Petty" , "Spiteful -- excellent (slang)" , "Aim - low - average" .)