Reptile, one moved to front in Guiana (6)
I believe the answer is:
iguana
'reptile' is the definition.
(iguana is a kind of reptile)
'one moved to front in guiana' is the wordplay.
'guiana' can be anagrammed to 'IGUANA'.
Though, I'm not sure how the anagram is indicated.
Can you help me to learn more?
(Other definitions for iguana that I've seen before include "cold-blooded customer!" , "Large crested lizard" , "Tropical tree-lizard" , "American lizard with a spiny crested back" , "Arboreal lizard of S America" .)