Requests time off from jobs (4)
I believe the answer is:
asks
'requests' is the definition.
('ask' can be a synonym of 'request')
'time off from jobs' is the wordplay.
'time' becomes 't' (abbreviation).
'off from' indicates named letters should be taken away.
'jobs' becomes 'tasks' ('task' can be a synonym of 'job').
'tasks' with 't' taken out is 'ASKS'.
(Other definitions for asks that I've seen before include "Inquiries" , "Poses a question" , "Makes an inquiry" , "Invites; enquires" , "Inquires (4)" .)