Residence in which all four turn up (5)
I believe the answer is:
'residence' is the definition.
(I know that villa is a type of house)
'all four turn up' is the wordplay.
'four' becomes 'IV' (Roman numerals).
'turn up' says the letters should be written in reverse.
'alliv' back-to-front is 'VILLA'.
'in which' acts as a link.
(Other definitions for villa that I've seen before include "Midlands football team" , "Roman or suburban house" , "Aston ..., English Premier League club" , "Type of house" , "A place in the country" .)