Resident of the U.S.'s second-largest city (8)
I believe the answer is:
angeleno
(Other definitions for angeleno that I've seen before include "man from LA" , "North American citizen" , "Native of LA" , "Californian" , "Man from west coast" .)
I believe the answer is:
angeleno
(Other definitions for angeleno that I've seen before include "man from LA" , "North American citizen" , "Native of LA" , "Californian" , "Man from west coast" .)