Resist, as Indian state profits start to tumble (2,7)
I believe the answer is:
go against
'resist' is the definition.
(I've seen this before)
'indian state profits start to tumble' is the wordplay.
'indian state' becomes 'goa' (Goa is a state of India).
'profits' becomes 'gains' ('gain' can be a synonym of 'profit').
'start to' indicates taking the first letters.
The first letter of 'tumble' is 't'.
'goa'+'gains'+'t'='GO AGAINST'
'as' acts as a link.
(Other definitions for go against that I've seen before include "disadvantage" , "Oppose" , "Counter" , "Turn out unfavourably (for)" , "Resist" .)