Resist horned creature (4)
I believe the answer is:
buck
This might be a double definition.
'resist' is the first definition.
(as in bucking a trend)
'horned creature' is the second definition.
'buck' can be an answer for 'creature' (buck is a kind of creature). I am unsure of the 'horned' bit.
Can you help me to learn more?
(Other definitions for buck that I've seen before include "Animal - dollar - responsibility" , "impetuous youth" , "vault" , "A slangy American dollar, may be fast" , "Blood < money" .)