Respect refusal to be constrained by time (6)
I believe the answer is:
honour
'respect' is the definition.
('honour' can be a synonym of 'respect')
'refusal to be constrained by time' is the wordplay.
'refusal' becomes 'no'.
'to be constrained by' means one lot of letters goes inside another.
'time' becomes 'hour' (hour is a kind of time).
'no' placed inside 'hour' is 'HONOUR'.
(Other definitions for honour that I've seen before include "Acclaim" , "Great esteem" , "Be faithful to; glory" , "prestigious award" , "Reputation" .)