Response concerning the deed (8)
I believe the answer is:
reaction
'response' is the definition.
(synonyms)
'concerning the deed' is the wordplay.
'concerning' becomes 're' (both can mean on a particular topic).
'the deed' becomes 'action' (I've seen this before).
're'+'action'='REACTION'
(Other definitions for reaction that I've seen before include "effect of drugs?" , "Answer" , "Feedback" , "Reflex; backlash" , "Chemical change or response" .)