Response from wife in tortuous snare (6)
I believe the answer is:
answer
'response' is the definition.
(I know that response can be written as answer)
'wife in tortuous snare' is the wordplay.
'wife' becomes 'w'.
'in' is an insertion indicator.
'tortuous' indicates anagramming the letters.
'snare' is an anagram of 'anser'.
'w' placed into 'anser' is 'ANSWER'.
'from' acts as a link.
(Other definitions for answer that I've seen before include "It could give you a" , "Reaction to a question" , "Be satisfactory" , "Response to a question" , "Acknowledge" .)