Response to Racine mixed (8)

I believe the answer is:

reaction

'response' is the definition.
(synonyms)

'to racine mixed' is the wordplay.
'mixed' is an anagram indicator.
'to'+'racine'='toracine'
'toracine' with letters rearranged gives 'REACTION'.

(Other definitions for reaction that I've seen before include "Reflex; backlash" , "Into care (anag)" , "Feedback" , "Answer" , "Chemical change or backlash" .)

I've seen this clue in The Times.

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