Rest needed by stand-up? Just the opposite (3,4)
I believe the answer is:
lie down
'rest' is the definition.
(to lie down is to have a short rest)
I don't understand the remainder of the clue.
Can you help me to learn more?
(Other definitions for lie down that I've seen before include "Take to one's bed" , "Put your feet up" , "Take rest; be submissive (under)" , "Short rest on a bed" , "Rest in a horizontal position" .)