Restless desire (4)
I believe the answer is:
<span class="explanation-format__ClueExplanation">'<span class="explanation-format__original">restless desire</span>' is the definition.<br/ ><span class="explanation-format__explanation">(as in having an itch for something)</span><br/ ><br/ >This is all the clue.<br/ ></span>
(Other definitions for itch that I've seen before include "Constant desire" , "Tingle" , "It needs to be scratched" , "Uncomfortable feeling" , "following seven years in union?" .)