Result at university -- second in fashion (6)
I believe the answer is:
upshot
'result' is the definition.
('upshot' can be a synonym of 'result')
'at university second in fashion' is the wordplay.
'at university' becomes 'up'.
'second' becomes 's' (common abbreviation).
'in fashion' becomes 'hot' (hot can mean current or trendy**).
'up'+'s'+'hot'='UPSHOT'
(Other definitions for upshot that I've seen before include "skier" , "Outcome, final result" , "Outcome of vertical discharge?" , "Event" , "anti-aircraft fire?" .)