Result of being against series (11)
I believe the answer is:
consequence
'result' is the definition.
(I know that result can be written as consequence)
'against series' is the wordplay.
'against' becomes 'con' (as in pros and cons, for and against).
'series' becomes 'sequence' (sequence is a kind of series).
'con'+'sequence'='CONSEQUENCE'
'of being' acts as a link.
(Other definitions for consequence that I've seen before include "Result, effect" , "Upshot" , "Outcome" , "Result; importance" , "Ensuing result" .)