Reverse out initially, heading off to the point (8)
I believe the answer is:
opposite
'reverse' is the definition.
(I know that reverse can be written as opposite)
'out initially heading off to the point' is the wordplay.
'out initially' becomes 'oppos' (I can't explain this - if you can you should believe this answer much more).
'heading off' means to remove the first letter.
'to the point' becomes 'site' (site is a kind of point).
'site' with its initial letter taken away is 'ite'.
'oppos'+'ite'='OPPOSITE'
Can you help me to learn more?
(Other definitions for opposite that I've seen before include "Adverse" , "Antithetical, vis-a-vis at" , "Contary of face-to-face" , "Corresponding" , "Oppose it, being faced against" .)