Rex and Victor in east somehow go without food (6)
I believe the answer is:
starve
'go without food' is the definition.
(I've seen this in another clue)
'rex and victor in east somehow' is the wordplay.
'rex' becomes 'R' (abbreviation e.g. GR=George Rex, King George).
'and' is a charade indicator (letters next to each other).
'victor' becomes 'V' (phonetic alphabet: alpha, bravo, charlie etc.).
'in' is an insertion indicator.
'somehow' indicates an anagram.
'r'+'v'='rv'
'east' with letters rearranged gives 'stae'.
'rv' going into 'stae' is 'STARVE'.
(Other definitions for starve that I've seen before include "Averts (anag)" , "Suffer from food deprivation" , "Vaster (anag)" , "Stop feeding" , "Suffer extreme hunger" .)