Rhone city (4)
I believe the answer is:
lyon
'rhone city' is the definition.
(I've seen this in another clue)
This is the entire clue.
(Other definitions for lyon that I've seen before include "River port, capital of the Rhone department" , "City of central France" , "French city on the Rhone" , "Southern French city" , "River port of southeast France" .)