Rich female leaves boozer (4)
I believe the answer is:
lush
'boozer' is the definition.
(synonyms)
'rich female leaves' is the wordplay.
'rich' becomes 'flush' (flush with cash).
'female' becomes 'f' (common abbreviation).
'leaves' is a deletion indicator.
'flush' with 'f' taken away is 'LUSH'.
(Other definitions for lush that I've seen before include "Of grass, growing thick and strong" , "Luxuriant; very rich" , "Habitual drinker (slang)" , "one wants a lot to drink" , "Handsome" .)