Right hand does wandering in island (6)
I believe the answer is:
rhodes
'island' is the definition.
(Greek island)
'right hand does wandering in' is the wordplay.
'right hand' becomes 'rh' (medical abbreviation).
'wandering' indicates anagramming the letters.
'in' is an insertion indicator.
'does' with letters rearranged gives 'odes'.
'rh' placed inside 'odes' is 'RHODES'.
(Other definitions for rhodes that I've seen before include "British financier and coloniser in southern Africa, d. 1902" , "Cycled round hot Society Island" , "Largest island of the Dodecanese" , "Shored (anag) - Greek island" , "She and Rod have a Greek holiday here" .)