Riles unfortunate man around city (9)
I believe the answer is:
marseille
'city' is the definition.
(Marseille is an example)
'riles unfortunate man around' is the wordplay.
'unfortunate' indicates anagramming the letters.
'man' becomes 'male' ().
'around' is an insertion indicator.
'riles' is an anagram of 'rseil'.
'rseil' put into 'male' is 'MARSEILLE'.
(Other definitions for marseille that I've seen before include "Major seaport of Southern France" , "French port" , "fabric" , "Port city of France" , "French city" .)