River runs north through garden (5)
I believe the answer is:
rhone
'river' is the definition.
(Rhone River is an example)
'runs north through garden' is the wordplay.
'runs' becomes 'r' (cricket abbreviation).
'north' becomes 'n' ('N' can be a synonym of 'north').
'through' indicates putting letters inside (I've seen this in other clues).
'garden' becomes 'hoe' (I've seen this in other clues).
'n' inserted inside 'hoe' is 'hone'.
'r'+'hone'='RHONE'
(Other definitions for rhone that I've seen before include "River flowing through Lake Geneva" , "wine-producing area" , "River running from the Swiss Alps to the Mediterranean" , "French flower" , "12 wine region" .)