Rodent disease contained by artificial intelligence (6)
I believe the answer is:
agouti
'rodent' is the definition.
(agouti is a kind of rodent)
'disease contained by artificial intelligence' is the wordplay.
'disease' becomes 'gout' (gout is a kind of disease).
'contained by' means one lot of letters goes inside another.
'artificial intelligence' becomes 'ai' ('AI' can be a synonym of 'artificial intelligence').
'gout' going within 'ai' is 'AGOUTI'.
(Other definitions for agouti that I've seen before include "Burrowing rodent - IOU tag (anag)" , "S.Amer. rodent" , "Rabbit-sized rodent of South America valued as food" , "Creature" , "S. American burrowing rodent" .)