Rogue's central part in place of worship, we hear (5)
I believe the answer is:
knave
'rogue's' is the definition.
('knave' can be a synonym of 'rogue')
'central part in place of worship we hear' is the wordplay.
'central part in place of worship' becomes 'nave'.
'we hear' shows a homophone (sound like).
'nave' sounds like 'KNAVE'.
(Other definitions for knave that I've seen before include "Jack - scoundrel" , "Dishonest man; jack" , "Jack (card); base fellow" , "sinner?" , "Rat" .)