Roman poet’s house and descendants (6)
I believe the answer is:
horace
'roman poet's' is the definition.
(Horace was a Roman poet)
'house and descendants' is the wordplay.
'house' becomes 'ho' (abbreviation for house).
'and' means one lot of letters go next to another.
'descendants' becomes 'race' (I can't explain this - if you can you should give a lot more credence to this answer).
'ho'+'race'='HORACE'
Can you help me to learn more?
(Other definitions for horace that I've seen before include "Latin ode writer" , "Odist" , "Roman poet and satirist" , "Boy's name - Roman poet" , "Roman poet; -- Walpole" .)