Rotter's wrong answer (6)

I believe the answer is:

retort

'answer' is the definition.
(I know that retort is a more specific form of the action answer)

'rotter's wrong' is the wordplay.
'wrong' indicates anagramming the letters.
'rotter' is an anagram of 'RETORT'.

(Other definitions for retort that I've seen before include "Chem. flask; sharp answer" , "Quick and clever or angry reply" , "Long-necked glass vessel" , "one used in lab" , "Sharp response; lab item" .)

I've seen this clue in the Evening Standard.

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