Round bees, very large (5)
I believe the answer is:
obese
'very large' is the definition.
(I've seen this before)
'round bees' is the wordplay.
I cannot quite understand how this works, but
'round' could be 'o' (round can mean a round object) and 'o' is found in the answer.
an anagram of 'bees' is 'bese' which is present in the answer.
No letters remain.
This may be the basis of clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for obese that I've seen before include "Carrying far too much weight" , "Morbidly overweight" , "Extremely fat" , "Very big" , "Unusually fat" .)