Rubbish effect of drug, ecstasy (5)
I believe the answer is:
tripe
'rubbish' is the definition.
(both can mean nonsense)
'effect of drug ecstasy' is the wordplay.
I cannot quite understand how this works, but
'drug' could be 'e' (E is another name for ecstasy) and 'e' is located in the answer.
The remaining letters 'trip' is a valid word which might be clued in a way I don't see.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for tripe that I've seen before include "Ruminant's stomach lining" , "Cow's stomach lining used as food" , "Edible lining of cow's stomach - rubbish" , "Rubbish (edible, maybe)" , "Rot" .)