Rude about space, first and last (6)
I believe the answer is:
endure
'last' is the definition.
(I know that last can be written as endure)
'rude about space first' is the wordplay.
'about' indicates anagramming the letters.
'space' becomes 'en' (in printing, a space as wide as a letter 'n').
'first' means one lot of letters go next to another.
'rude' with letters rearranged gives 'dure'.
'dure' put after 'en' is 'ENDURE'.
'and' acts as a link.
(Other definitions for endure that I've seen before include "Bear something patiently" , "Abide" , "brook" , "Bear, stick it out" , "Suffer, tolerate" .)