Ruined English female sheltered by benefactor (4,3)
I believe the answer is:
done for
'ruined' is the definition.
(synonyms)
'english female sheltered by benefactor' is the wordplay.
'english' becomes 'E' (abbreviation).
'female' becomes 'f' (abbreviation).
'sheltered by' is an insertion indicator.
'benefactor' becomes 'donor' (donor is a kind of benefactor).
'e'+'f'='ef'
'ef' inserted into 'donor' is 'DONE FOR'.
(Other definitions for done for that I've seen before include "finished" , "killed" , "Dead - almost dead" , "Sunk" , "condemned" .)