Ruined; ran (6)
I believe the answer is:
dashed
I believe this clue is a double definition.
'ruined' is the first definition.
(dash can mean to ruin or destroy)
'ran' is the second definition.
(dashing is a kind of running)
(Other definitions for dashed that I've seen before include "Flaming" , "Thrown to the ground, as hopes may be" , "Darted headlong" , "hurled at" , "completely destroyed" .)