Ruined through one being got rid of (8)
I believe the answer is:
perished
'ruined' is the definition.
(I've seen this before)
'through one being got rid of' is the wordplay.
'through' becomes 'per' ('per' can mean through or by means of).
'one' becomes 'i' (Roman numeral).
'being got rid of' becomes 'shed' (shed can mean to lose or cast off).
'per'+'i'+'shed'='PERISHED'
(Other definitions for perished that I've seen before include "(Of rubber) forty three" , "dead - with 15a" , "Extremely cold - died - rotted" , "Died, failed" , "Decayed, died" .)