Rule can become related to fission (7)
I believe the answer is:
nuclear
'fission' is the definition.
(synonyms)
'rule can become' is the wordplay.
'become' indicates anagramming the letters.
'rule'+'can'='rulecan'
'rulecan' is an anagram of 'NUCLEAR'.
'related to' is the link.
I am not very happy about this link. Some or all of it may belong to another bit of the clue.
Can you help me to learn more?
(Other definitions for nuclear that I've seen before include "type of power supply" , "Type of energy" , "Concerning subatomic particles" , "Such power available" , "Involving part of an atom" .)