Rule from base off Bering Sea (5)
I believe the answer is:
reign
'rule' is the definition.
(reign is a kind of rule)
'from base off bering sea' is the wordplay.
'from' indicates anagramming the letters (from the letters).
'off' is a deletion indicator.
'bering'+'sea'='beringsea'
'beringsea' with 'base' removed is 'ringe'.
'ringe' with letters rearranged gives 'REIGN'.
(Other definitions for reign that I've seen before include "Govern" , "Rule over in Niger" , "Have sovereign power" , "Time on throne" , "Monarch's period" .)